An international consensus statement was produced which sets out the criteria for diagnosing APS;
- one or more clinical episodes of arterial, venous or small-vessel thrombosis in any tissue or organ confirmed by findings from imaging studies,
Doppler studies, or histopathology:
- Thrombosis may involve the cerebral vascular system, coronary arteries, pulmonary system (emboli or thromboses), arterial or venous
system in the extremeties, hepatic veins, renal veins, ocular arteries or veins, or adrenal glands.
or
- One or more late-term (more than ten weeks gestation) spontaneous miscarriage or
- One or more premature birth of a healthy neonate at or before 34 weeks because of severe precampsia, eclampsia or severe placental insufficiency or
- Three or more unexplained, consecutive spontaneous miscarriages before 10 week's gestation.
The report also specifies that the patient must have two positive blood tests twelve weeks apart. The time interval is meant to remove the possibility
that anti-phospholipid antibodies are present as a result of infection and will soon dissipate.
